The differences between datasets are because sample sizes are much larger and data on vaccine effects span a longer time period after full vaccination in the latter than in the former. Hence, the longer, least optimistic estimate is the most likely. This is why vaccination cost-benefit analyses favour vaccination only against organisms with stable genomes, meaning with low mutation rates. RNA genomes are the most mutable ones known. A priori, the Israeli RNA-based vaccination has several potential risks. Vaccination works as a prophylactic. Vaccination of individuals while they are exposed to a pandemic has several adverse consequences.
1. Vaccination processes usually imply temporary immune system weakening, before vaccine-induced immunity is acquired. Hence, the vaccinated are fragilized during the vaccination process, and more likely to develop any diseases against which the immune system usually defends the body. This includes any viral and bacterial infections, and individual cancer cells that would escape extermination by the immune system during this vaccination-induced weakened period. This could cause cancer in the medium- or long-term.
2. In the long-term, the antibodies induced by the RNA vaccine will cause autoimmune reactions to the cells producing the viral protein encoded by the vaccine RNA, and to cells with natural human proteins resembling the viral protein encoded by the vaccine RNA.
3. Massive vaccination might select vaccine-resistant viral variants with likely catastrophic effects, especially on the vaccinated.
4. RNA from the vaccine will in some cases integrate chromosomes of the vaccinated, with potentially harmful consequences difficult to evaluate at this point. Any claim to the contrary is misleading and misinformed. Human chromosomes integrated genomes of retroviruses that include RNA->DNA reverse transcriptase genes. This was the topic of the 1976 Nobel prize in Physiology and could not be ignored by competent professionals. Reanalyses of two separate bodies of data, one published by the Israel Ministry of Health (Table 1) and one by the team of Dan Balicer from Clalit (our reanalyses of data from Dagan et al 2021), indicate adverse effects due to the 5-week vaccination process, as compared to the unvaccinated. Eight among ten authors of Dagan et al disclose receiving funds for other projects from Pfizer. Pfizer is also a main funder of the Israeli Ministry of Health. Hence, these are not unbiased, neutral and independent bodies, which is required for any study, and especially studies with such crucial consequences.
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